Challenges to multiple testing in clinical trials

DOI10.1002/BIMJ.200900206MaRDI QIDQ3076078zbMATH OpenOpenAlexWikidataFDO

Authors H. M. James Hung, Sue-Jane Wang

Publication date 17 February 2011

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/bimj.200900206

zbMATH Keywords

composite endpointfamilywisenon-inferioritysequentially rejectivestudywise

Mathematics Subject Classification ID

Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(17)

• Assessing additional benefit in noninferiority trials
• Note on simultaneous inferences about non-inferiority and superiority for a primary and a secondary endpoint
• Power calculations in clinical trials with complex clinical objectives
• Simultaneous and selective inference: Current successes and future challenges
• scientific article; zbMATH DE number 3947446 (Why is no real title available?)
• A Decision Rule for Evaluating Several Independent Clinical Trials Collectively
• Panel forum on multiple comparison procedures: A commentary from a complex trial design and analysis plan
• Partition testing in confirmatory adaptive designs with structured objectives
• Multiple comparisons in complex clinical trial designs
• Handbook of multiple comparisons
• Simultaneous tests of non inferiority and superiority in three-arm clinical studies with heterogeneous variance
• Advanced multiplicity adjustment methods in clinical trials
• Graphical approaches using a Bonferroni mixture of weighted Simes tests
• Key multiplicity issues in clinical drug development
• Memory and other properties of multiple test procedures generated by entangled graphs
• Changes are still needed on multiple co-primary endpoints
• Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests

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