Comparison of different approaches for dose response analysis

DOI10.1002/BIMJ.201700276MaRDI QIDQ4626710zbMATH OpenOpenAlexWikidataFDO

Authors Saswati Saha, Werner Brannath

Publication date 28 February 2019

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://zenodo.org/record/2564007

zbMATH Keywords

dose finding studieslog likelihood modelsMCP-modmodel selection

Mathematics Subject Classification ID

Statistical ranking and selection procedures (62F07) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

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• BMA‐Mod: A Bayesian model averaging strategy for determining dose‐response relationships in the presence of model uncertainty
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• Multiple testing for dose finding

Cites work

• Analysis of Randomized Dose‐Finding‐Studies: Closure Test Modifications Based on Multiple Contrast Tests
• Asymptotics for likelihood ratio tests under loss of identifiability
• Bayesian Nonparametric Estimation of Continuous Monotone Functions with Applications to Dose–Response Analysis
• Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies
• Dose response signal detection under model uncertainty
• Elliptically contoured models in statistics and portfolio theory
• scientific article; zbMATH DE number 3990600 (Why is no real title available?)
• scientific article; zbMATH DE number 48335 (Why is no real title available?)
• Likelihood ratio tests for a dose-response effect using multiple nonlinear regression models
• Mixture models: theory, geometry and applications
• Multiple Test Procedures for Dose Finding
• Multiple Test Procedures for Identifying the Minimum Effective and Maximum Safe Doses of a Drug
• On the Distribution of the Likelihood Ratio
• Optimal designs for dose-finding studies
• Optimal Tests when a Nuisance Parameter is Present Only Under the Alternative
• Testing effect of a drug using multiple nested models for the dose-response
• Testing the Statistical Certainty of a Response to Increasing Doses of a Drug

Cited in

(5)

• Dose finding in drug development.
• Testing effect of a drug using multiple nested models for the dose-response
• A multiple comparison procedure for dose-finding trials with subpopulations
• Power and sample size for dose-finding studies with survival endpoints under model uncertainty
• Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies

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• bnpmr

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