Multiple Test Procedures for Identifying the Minimum Effective and Maximum Safe Doses of a Drug

DOI10.1198/016214502753479428MaRDI QIDQ4468385zbMATH OpenOpenAlexWikidataFDO

Authors Ajit C. Tamhane, Brent R. Logan

Publication date 10 June 2004

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1198/016214502753479428

Mathematics Subject Classification ID

Multivariate distribution of statistics (62H10) Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(11)

• Identification of the minimum non-inferior dose in a three-arm non-inferiority trial
• Generalized fiducial inference for threshold estimation in dose-response and regression settings
• Asymptotics for p-value based threshold estimation under repeated measurements
• Multiple testing for identifying effective and safe treatments
• A Two-Stage Stepwise Estimation Procedure
• Multiple Test Procedures for Identifying the Maximum Safe Dose
• IDENTIFYING THE MAXIMUM SAFE DOSE: A MULTIPLE TESTING APPROACH
• Comparison of different approaches for dose response analysis
• Analyzing Randomized Dose Finding Studies with a Primary and a Secondary Endpoint
• Spline-based procedures for dose-finding studies with active control
• Identifying therapeutic window for the ratio of means under heteroscedasticity

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