Computing posterior probabilities for score-based alignments using ppALIGN

DOI10.1515/1544-6115.1702MaRDI QIDQ2922545zbMATH OpenOpenAlexWikidataFDO

Authors Stefan Wolfsheimer, Ralf Rabus, Gregory Nuel, Alexander Hartmann

Publication date 13 October 2014

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1515/1544-6115.1702

zbMATH Keywords

posterior distributionBLASTlocal scoreforward/ backwardglobal scorepair-HMM

Mathematics Subject Classification ID

Protein sequences, DNA sequences (92D20)

Recommendations

• Toward an accurate statistics of gapped alignments
• Rapid and accurate estimates of statistical significance for sequence data base searches.
• Simple and Fast Inverse Alignment
• Upper bounds and importance sampling of \(p\)-values of DNA and protein sequence alignments
• Statistics of optimal sequence alignments.

Cited in

(2)

• Improving Profile-Profile Alignments via Log Average Scoring
• Duality between the local score of one sequence and constrained hidden Markov model

Describes a project that uses

Uses Software

• Bali-phy
• Rose
• HMMoC
• Statalign
• Clustal X
• CLUSTAL
• ppALIGN

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