Conformal mapping in optical biosensor applications

DOI10.1007/S00285-014-0827-2MaRDI QIDQ493074zbMATH OpenOpenAlexWikidataFDO

Authors Matthew E. Zumbrum, David A. Edwards

Publication date 11 September 2015

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-014-0827-2

zbMATH Keywords

conformal mappingFlexchipoptical biosensorssurface-volume reactions

Mathematics Subject Classification ID

Conformal mappings of special domains (30C20) Asymptotic expansions of solutions to PDEs (35C20) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Review text

Optical biosensors used to investigate surface-volume reaction kinetics are usually modeled assuming unidirectional flow within these devices. New versions of these biosensors (e.g. Flexchip) include more complicated geometry and two-dimensional flows. The authors attempt to model these flows by relating them to unidirectional flows with the use of conformal mappings.

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Cites work

• Algorithm 843
• Effective rate models for the analysis of transport-dependent biosensor data
• Estimating rate constants in a convection-diffusion system with a boundary reaction
• Functions of a Complex Variable: Theory and Technique
• The effect of a receptor layer on the measurement of rate constants
• Transport effects on surface reaction arrays: biosensor applications

Cited in

(4)

• Transport effects on multiple-component reactions in optical biosensors
• Receptor heterogeneity in optical biosensors
• Optical Conformal Mapping
• Multiple surface reactions in arrays with applications to optical biosensors

Describes a project that uses

Uses Software

• SC Toolbox
• Schwarz-Christoffel

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