Dose finding with longitudinal data: simpler models, richer outcomes

DOI10.1002/SIM.6552MaRDI QIDQ6903175zbMATH OpenFDO

Authors Xavier Paoletti, Adélaïde Doussau, Monia Ezzalfani, Elisa Rizzo, Rodolphe Thiébaut

Publication date 10 November 2025

Published in Statistics in Medicine (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/SIM.6552

zbMATH Keywords

binarycontinual reassessment methodmisspecifiedordinal

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

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• Miscellanea. A stopping rule for the continual reassessment method
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• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
• Small-Sample Confidence Sets for the MTD in a Phase I Clinical Trial
• Statistical Methods for Dose‐Finding Experiments
• The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Quasi‐Likelihood Approach
• Utility-Based Optimization of Combination Therapy Using Ordinal Toxicity and Efficacy in Phase I/II Trials

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