Estimation of HIV burden through Bayesian evidence synthesis
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Abstract: Planning, implementation and evaluation of public health policies to control the human immunodeficiency virus (HIV) epidemic require regular monitoring of disease burden. This includes the proportion living with HIV, whether diagnosed or not, and the rate of new infections in the general population and in specific risk groups and regions. Estimation of these quantities is not straightforward: data informing them directly are not typically available, but a wealth of indirect information from surveillance systems and ad hoc studies can inform functions of these quantities. In this paper we show how the estimation problem can be successfully solved through a Bayesian evidence synthesis approach, relaxing the focus on "best available" data to which classical methods are typically restricted. This more comprehensive and flexible use of evidence has led to the adoption of our proposed approach as the official method to estimate HIV prevalence in the United Kingdom since 2005.
Recommendations
- Bayesian evidence synthesis for a transmission dynamic model for HIV among men who have sex with men
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Cites work
- Bayesian evidence synthesis for a transmission dynamic model for HIV among men who have sex with men
- scientific article; zbMATH DE number 1134987 (Why is no real title available?)
- Modeling of the HIV infection epidemic in the Netherlands: a multi-parameter evidence synthesis approach
- Sampling and Bayes' Inference in Scientific Modelling and Robustness
Cited in
(8)- A numerically stable algorithm for integrating Bayesian models using Markov melding
- Synthesising evidence to estimate pandemic (2009) A/H1N1 influenza severity in 2009--2011
- Bayesian evidence synthesis for a transmission dynamic model for HIV among men who have sex with men
- Estimating prevalence using indirect information and Bayesian evidence synthesis
- Value of information: sensitivity analysis and research design in Bayesian evidence synthesis
- Evidence synthesis for stochastic epidemic models
- A review of methods for research synthesis
- Probabilistic projections of HIV prevalence using Bayesian melding
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