Exploratory subgroup analysis in clinical trials by model selection

DOI10.1002/BIMJ.201500147MaRDI QIDQ112662zbMATH OpenOpenAlexWikidataFDO

Authors Gerd K. Rosenkranz

Publication date 27 May 2016

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/bimj.201500147

zbMATH Keywords

bootstrapselection biasbias reductionestimation after selectiononcologyresampling approachselection uncertaintyselective inferencesubgroup selection

Mathematics Subject Classification ID

Bootstrap, jackknife and other resampling methods (62F40) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Inference on Selected Subgroups in Clinical Trials
• Adjusting for selection bias in assessing treatment effect estimates from multiple subgroups
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• Subgroup-effects models for the analysis of personal treatment effects

Cites work

• scientific article; zbMATH DE number 6378123 (Why is no real title available?)
• scientific article; zbMATH DE number 3385132 (Why is no real title available?)
• Analyzing bagging
• Bagging predictors
• Bootstrap corrections of treatment effect estimates following selection
• Estimating the dimension of a model
• Estimation and accuracy after model selection
• Models for discrete longitudinal data.
• Statistical learning and selective inference
• The Impact of Dichotomization on the Efficiency of Testing for an Interaction Effect in Exponential Family Models

Cited in

(12)

• Protocol Designed Subgroup Analyses in Multiarmed Clinical Trials: Multiplicity Aspects
• Treatment effect heterogeneity for univariate subgroups in clinical trials: shrinkage, standardization, or else
• Optimal subgroup selection
• Exploratory subgroup identification in the heterogeneous Cox model: a relatively simple procedure
• subtee
• Assessing the Most Vulnerable Subgroup to Type II Diabetes Associated with Statin Usage: Evidence from Electronic Health Record Data
• Subgroup identification and variable selection for treatment decision making
• Inference on Selected Subgroups in Clinical Trials
• Modern approaches for evaluating treatment effect heterogeneity from clinical trials and observational data
• A Bayesian subgroup analysis using collections of ANOVA models
• Adjustment for exploratory cut-off selection in randomized clinical trials with survival endpoint
• REPRESENTING THE RESULTS OF SUBGROUP ANALYSIS IN COMPARATIVE CLINICAL STUDIES BY A GRAPH

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