Feedback-induced complex dynamics in a two-component regulatory circuit
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Periodic solutions to ordinary differential equations (34C25) Complex behavior and chaotic systems of ordinary differential equations (34C28) Qualitative investigation and simulation of ordinary differential equation models (34C60) Stability of solutions to ordinary differential equations (34D20) Feedback control (93B52)
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Cites work
- An introduction to systems biology. Design principles of biological circuits.
- Birhythmicity, chaos, and other patterns of temporal self-organization in a multiply regulated biochemical system.
- Designer gene networks: Towards fundamental cellular control
- Necessary conditions for multistationarity and stable periodicity
Cited in
(20)- Dynamics of the interlocked positive feedback loops explaining the robust epigenetic switching in \textit{Candida albicans}
- Feedback loops interlocked at competitive binding sites amplify and facilitate genetic oscillations
- Feedbacks, nonlinearities and nonequilibria: a thermodynamic perspective
- Dynamics of complex feedback architectures in metabolic pathways
- Evolution of complex probability distributions in enzyme cascades
- Birhythmicity and hard excitation from coupled synthetic feedback loops
- Identification of feedback loops embedded in cellular circuits by investigating non-causal impulse response components
- Two-component feedback loops and deformed mechanics
- Switching between oscillations and homeostasis in competing negative and positive feedback motifs
- The role of feedback mechanisms in biological network models -- a tutorial
- Comparison of dynamical behaviors between monofunctional and bifunctional two-component signaling modules
- Positive feedbacks contribute to the robustness of the cell cycle with respect to molecular noise
- Feedback loops shape cellular signals in space and time
- Asymmetric transition and time-scale separation in interlinked positive feedback loops
- Noise-induced bistable switching dynamics through a potential energy landscape
- Type-dependent stochastic Ising model describing the dynamics of a non-symmetric feedback module
- Complex dynamical analysis of a coupled network from innate immune responses
- A simple regulatory circuit that can simultaneously generate excitability of two different mechanisms
- Negative feedback contributes to the stochastic expression of the interferon-\(\beta\) gene in virus-triggered type I interferon signaling pathways
- Multistability, oscillations and bifurcations in feedback loops
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