Introduction to mathematical methods in bioinformatics.

MaRDI QIDQ1881358zbMATH OpenFDO

Authors A. V. Isaev

Publication date 4 October 2004

Published in Universitext (Search for Journal in Brave)

Mathematics Subject Classification ID

Computing methodologies and applications (68U99) Introductory exposition (textbooks, tutorial papers, etc.) pertaining to biology (92-01) General biology and biomathematics (92B05) Biochemistry, molecular biology (92C40)

Review text

Bioinformetics can be defined as a collection of mathematical, statistical and computational methods for analyzing biological sequences. The book has two parts corresponding to two courses. The first part is ``Sequence Analysis and contains the following chapters: 1. Introduction; 2. Sequence Alignment; 3. Markov Chains and Hidden Markov Models; 4. Protein Folding; 5. Phylogenetic Reconstruction. The second part is ``Mathematical Background for Sequence Analysis with the chapters: 6. Elements of Probability Theory; 7. Significance of Sequence Allignment Scores; 8. Elements of Statistics; 9. Substitution Matrices. The chapters 6 and 8 contain very few proofs. Without reading Part II, one's understanding, of various procedures from Part I will be incomplete. But, the chapters 4 and 5 could each easily be expanded into a separate a book. The book concentrates on the mathematical basics of bioinformatics rather than on recent progress in the area. It is a comprehensive guide to bioinformatics, which takes into account that a bioinformatician should be able not only to use software packages, but also to know the mathematics behind these packages.

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Cited in

(18)

• Methods of bioinformatics. An introduction.
• What has mathematics done for biology?
• Mathematics of genome analysis
• Mathematics of bioinformatics. Theory, methods and applications.
• Invitation to protein sequence analysis through probability and information
• Sequence alignment in bioinformatics
• Problems and Solutions in Biological Sequence Analysis
• Introduction to bioinformatics.
• MATHEMATICAL APPROACH TO BIO-INFORMATICS
• scientific article; zbMATH DE number 1222686 (Why is no real title available?)
• Biological Sequence Analysis
• scientific article; zbMATH DE number 2172892 (Why is no real title available?)
• Bioinformatics and the Cell
• scientific article; zbMATH DE number 2189177 (Why is no real title available?)
• Some mathematical methods in the analysis of biological sequences
• Bioinformatics
• Dimensionality reduction and topographic mapping of binary tensors
• Theory and mathematical methods in bioinformatics

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