On a nonlinear model for tumor growth in a cellular medium (Q1679043)

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On a nonlinear model for tumor growth in a cellular medium
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    On a nonlinear model for tumor growth in a cellular medium (English)
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    8 November 2017
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    This article is concerned with an analytical study of a nonlinear model for tumor growth within a cellular medium. The governing system is given by a multi-phase flow of cancer cells. The evolution of tumor growth occurs in the presence of proliferating and quiescent cells as well as waste and a nutrient. The tumor is modeled as a growing, time-dependent domain \(\Omega\) with boundary \(\partial\Omega\). The total density of cancerous cells is allowed to vary. The authors obtain global-in-time weak solutions for this tumor growth model. They explain that their approach makes use of ``penalization of the boundary behavior, diffusion, viscosity and pressure in the weak formulation as well as convergence and compactness arguments (...).''
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    tumor growth models
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    cancer progression
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    mixed models
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    moving domain
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    penalization
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    existence
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