Qualitative analysis of a fractional model for HBV infection with capsids and adaptive immunity (Q2162126)
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scientific article; zbMATH DE number 7568628
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| English | Qualitative analysis of a fractional model for HBV infection with capsids and adaptive immunity |
scientific article; zbMATH DE number 7568628 |
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Qualitative analysis of a fractional model for HBV infection with capsids and adaptive immunity (English)
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5 August 2022
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Summary: This paper presents a mathematical model governed by fractional differential equations (FDEs) that describes the dynamics of hepatitis B virus (HBV) infection in within human body. The FDE model takes into account the HBV DNA-containing capsids, and the adaptive immunity mediated by cytotoxic T lymphocytes (CTL) cells and antibodies. Also, the incidence of infection is presented by Hattaf-Yousfi functional response that includes various forms existing in the literature. Moreover, the qualitative properties of the FDE model is rigorously established. Finally, numerical simulations are presented to support the theoretical results.
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HBV infection
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adaptive immunity
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fractional differential equations
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Caputo fractional derivative
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Hattaf-Yousfi functional response
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global dynamics
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0.8753869533538818
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0.8683645129203796
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0.8673399686813354
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0.8529568314552307
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