Qualitative analysis of a fractional model for HBV infection with capsids and adaptive immunity

DOI10.1504/IJDSDE.2022.123410MaRDI QIDQ2162126zbMATH OpenOpenAlexWikidataFDO

Authors Moussa Bachraoui, Khalid Hattaf, Noura Yousfi

Publication date 5 August 2022

Published in International Journal of Dynamical Systems and Differential Equations (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1504/ijdsde.2022.123410

zbMATH Keywords

adaptive immunityCaputo fractional derivativefractional differential equationsglobal dynamicsHattaf-Yousfi functional responseHBV infection

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Epidemiology (92D30)

Review text

Summary: This paper presents a mathematical model governed by fractional differential equations (FDEs) that describes the dynamics of hepatitis B virus (HBV) infection in within human body. The FDE model takes into account the HBV DNA-containing capsids, and the adaptive immunity mediated by cytotoxic T lymphocytes (CTL) cells and antibodies. Also, the incidence of infection is presented by Hattaf-Yousfi functional response that includes various forms existing in the literature. Moreover, the qualitative properties of the FDE model is rigorously established. Finally, numerical simulations are presented to support the theoretical results.

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(7)

• Global analysis and simulation of a fractional order HBV immune model
• Analysis of a fractional reaction-diffusion HBV model with cure of infected cells
• Mathematical analysis of Hepatitis C Virus infection model in the framework of non-local and non-singular kernel fractional derivative
• Spatiotemporal dynamics of fractional hepatitis B virus infection model with humoral and cellular immunity
• Modeling the memory and adaptive immunity in viral infection
• A Fractional Order Model for HBV Infection with Capsids and Cure Rate
• Mathematical Modeling of HBV Infection with DNA-Containing Capsids and Therapy

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