Nonlinear dynamics and noise actuated by the cycle of gene inactivation in stochastic transcription (Q2213859)
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English | Nonlinear dynamics and noise actuated by the cycle of gene inactivation in stochastic transcription |
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Nonlinear dynamics and noise actuated by the cycle of gene inactivation in stochastic transcription (English)
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3 December 2020
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The authors describe the stochastic process of on/off gene switching by integrating the inactivation cycle with mRNA birth and death processes. Following a comprehensive overview of the state-of-art of the mathematical modeling, they focus on several aspects, such as the regulation of non-monotonic transcription dynamics through gene inactivation recycling (Section 3) and the transcription noise at steady state (Section 4). Section 5 contains detailed proofs of the main results.
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stochastic gene transcription
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signalling transduction
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non-monotonic dynamics
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noise
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