Conformational B-A-transition in the DNA molecule model (Q6600436)

As is known the functioning of the genetic apparatus of biological systems is largely due to conformational changes in the DNA molecule and the native form of DNA is the B-form. However, under natural conditions, structural transitions from the B form to the A-form and vice versa are possible [\textit{J. D. Watson} et al., Molecular biology of the gene. Pearson (2004)]. In this article the authors have considered the Peyrard-Bishop model of DNA with an asymmetric double-well potential of interaction between nucleotides, taking into account friction. It is shown that at a certain value of the dissipation coefficient in this model, a kink-type solution is possible, which can be interpreted as a B-A transition [\textit{F. K. Zakir'yanov} and \textit{M. I. Fakhretdinov}, Izv. Vyssh. Uchebn. Zaved., Prikl. Nelineĭn. Din. 18, No. 1, 80--87 (2010; Zbl 1224.35405)]. Numerical estimates of the constructed solution are derived, and they qualitatively match estimates from prior studies.\N\NFor the entire collection see [Zbl 1520.92003].