Jackstraw inference for AJIVE data integration

DOI10.1016/J.CSDA.2022.107649MaRDI QIDQ6167041zbMATH OpenFDO

Authors Xi Yang, Katherine A. Hoadley, Jan Hannig, J. S. Marron

Publication date 7 July 2023

Published in Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2109.12272

zbMATH Keywords

data integrationjackstrawAJIVEstatistically significant

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08)

Abstract: In the age of big data, data integration is a critical step especially in the understanding of how diverse data types work together and work separately. Among data integration methods, the Angle-Based Joint and Individual Variation Explained (AJIVE) approach is particularly attractive because it not only studies joint behavior but also individual behavior. Typically AJIVE scores indicate important relationships between data objects, such as clusters. An important challenge is understanding which features, i.e. variables, are associated with those relationships. This challenge is addressed by the proposal of a hypothesis test for assessing statistical significance of features. The new test is inspired by the related jackstraw method developed for Principal Component Analysis. We use a high-dimensional muti-genomic cancer data set as our strong motivation and deep illustration of the methodology.

Recommendations

• Angle-based joint and individual variation explained
• Joint and individual variation explained (JIVE) for integrated analysis of multiple data types
• Feature selection for data integration with mixed multiview data
• sJIVE: supervised joint and individual variation explained

Cites work

• scientific article; zbMATH DE number 720689 (Why is no real title available?)
• scientific article; zbMATH DE number 3026527 (Why is no real title available?)
• Angle-based joint and individual variation explained
• Bounded probability properties of Kolmogorov-Smirnov and similar statistics for discrete data
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Cited in

(1)

• Rejoinder on: ``Data integration via analysis of subspaces (DIVAS)

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