Large‐Scale Statistical Parameter Estimation in Complex Systems with an Application to Metabolic Models

DOI10.1137/050644860MaRDI QIDQ5432419zbMATH OpenOpenAlexFDO

Authors Erkki Somersalo, Daniela Calvetti

Publication date 3 January 2008

Published in Multiscale Modeling & Simulation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/050644860

zbMATH Keywords

Bayesian statisticsischemia modellingMarkov chain Monte CarloMichaelis-Menten kineticsmulticompartment modeloptimizationsample-based priorskeletal muscle

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05) Physiology (general) (92C30) Biochemistry, molecular biology (92C40)

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Cited in

(15)

• Evaluation of an S-system root-finding method for estimating parameters in a metabolic reaction model
• Diverse metabolic model parameters generate similar methionine cycle dynamics
• Bayesian flux balance analysis applied to a skeletal muscle metabolic model
• Complexity analysis and parameter estimation of dynamic metabolic systems
• High-dimensional Bayesian parameter estimation: case study for a model of JAK2/STAT5 signaling
• Dynamic Bayesian sensitivity analysis of a myocardial metabolic model
• Vectorized and parallel particle filter SMC parameter estimation for stiff ODEs
• Parameter estimation for metabolic networks with two stage Bregman regularization homotopy inversion algorithm
• Bayesian stationary state flux balance analysis for a skeletal muscle metabolic model
• Variational data assimilation using targetted random walks
• Sampling-Based Analysis of a Spatially Distributed Model for Liver Metabolism at Steady State
• Modeling HIV-1 dynamics and fitness in cell culture across scales
• An Uncertainty-Weighted Asynchronous ADMM Method for Parallel PDE Parameter Estimation
• Dynamic activation model for a glutamatergic neurovascular unit
• The metabolic network of \textit{Clostridium acetobutylicum}: comparison of the approximate Bayesian computation via sequential Monte Carlo (ABC-SMC) and profile likelihood estimation (PLE) methods for determinability analysis

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