Mathematical modeling of p53 pulses in G2 phase with DNA damage

DOI10.1016/J.AMC.2014.01.120MaRDI QIDQ1646200zbMATH OpenOpenAlexFDO

Authors L. W. Zhang, Y. M. Cheng, K. M. Liew

Publication date 22 June 2018

Published in Applied Mathematics and Computation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.amc.2014.01.120

zbMATH Keywords

dynamicsmathematical modelingcheckpointsDNA damageG2 phasep53

Mathematics Subject Classification ID

Protein sequences, DNA sequences (92D20)

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Cites work

• A mathematical analysis of DNA damage induced G2 phase transition
• A simple time delay model for eukaryotic cell cycle
• Cellular responding DNA damage: An improved modeling of P53 gene regulatory networks under ion radiation (IR)

Cited in

(11)

• A mathematical analysis of DNA damage induced G2 phase transition
• Single stranded-DNA detection: the role of Wip1 in ATR-dependent pathway
• A mathematical study of the robustness of G2/M regulatory network in response to DNA damage with parameters sensitivity
• Oscillations and DNA repair in a spatio-temporal model of the p53 signalling pathway
• A predictive mathematical model of the DNA damage G2 checkpoint
• A mathematical model for the effect of low-dose radiation on the G2/M transition
• ATM and ATR activation through crosstalk between DNA damage response pathways
• Numerical solution of nonlinear Klein-Gordon equation using the element-free KP-Ritz method
• Mathematical modelling of p53 basal dynamics and DNA damage response
• Cellular responding DNA damage: An improved modeling of P53 gene regulatory networks under ion radiation (IR)
• A comprehensive complex systems approach to the study and analysis of mammalian cell cycle control system in the presence of DNA damage stress

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