Parsimonious Clone Tree Reconciliation in Cancer.

DOI10.4230/LIPICS.WABI.2021.9MaRDI QIDQ6133871zbMATH OpenOpenAlexFDO

Authors Palash Sashittal, Simone Zaccaria, Mohammed El-Kebir

Publication date 24 July 2023

Full work available at URL https://doi.org/10.4230/lipics.wabi.2021.9

zbMATH Keywords

intra-tumor heterogeneitymixed integer linear programmingphylogenetics

Mathematics Subject Classification ID

Mixed integer programming (90C11) Computational methods for problems pertaining to biology (92-08) Pathology, pathophysiology (92C32) Protein sequences, DNA sequences (92D20)

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Cited in

(7)

• Copy-number evolution problems: complexity and algorithms
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• TreeClone: reconstruction of tumor subclone phylogeny based on mutation pairs using next generation sequencing data
• Tumor copy number deconvolution integrating bulk and single-cell sequencing data
• Ancestral inference in tumors: how much can we know?
• Joint analysis of single-cell and bulk tissue sequencing data to infer intratumor heterogeneity
• Reconstructing mutational history in multiply sampled tumors using perfect phylogeny mixtures

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