Reconstructing mutational history in multiply sampled tumors using perfect phylogeny mixtures

DOI10.1007/978-3-662-44753-6_27MaRDI QIDQ5265099zbMATH OpenOpenAlexFDO

Authors Iman Hajirasouliha, Benjamin J. Raphael

Publication date 22 July 2015

Published in Lecture Notes in Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-662-44753-6_27

zbMATH Keywords

graph coloringDNA sequencingperfect phylogenycancer genomics

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15) Computational difficulty of problems (lower bounds, completeness, difficulty of approximation, etc.) (68Q17) Coloring of graphs and hypergraphs (05C15) Computational methods for problems pertaining to biology (92-08)

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Cited in

(7)

• Phyolin: identifying a linear perfect phylogeny in single-cell DNA sequencing data of tumors
• Joint inference of repeated evolutionary trajectories and patterns of clonal exclusivity or co-occurrence from tumor mutation trees
• Finding a perfect phylogeny from mixed tumor samples
• Copy-number evolution problems: complexity and algorithms
• Parameterized Complexity for Finding a Perfect Phylogeny from Mixed Tumor Samples
• Parsimonious Clone Tree Reconciliation in Cancer.
• Character-based phylogeny construction and its application to tumor evolution

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