Joint inference of repeated evolutionary trajectories and patterns of clonal exclusivity or co-occurrence from tumor mutation trees

DOI10.1007/978-3-031-04749-7_21zbMATH Open1496.92070OpenAlexW4285205220MaRDI QIDQ2170163FDOQ2170163

Authors: Xiang Ge Luo, Jack Kuipers, Niko Beerenwinkel 

Publication date: 30 August 2022

Full work available at URL: https://doi.org/10.1007/978-3-031-04749-7_21

Recommendations

• TreeClone: reconstruction of tumor subclone phylogeny based on mutation pairs using next generation sequencing data
• Reconstructing mutational history in multiply sampled tumors using perfect phylogeny mixtures
• Statistical inference for the evolutionary history of cancer genomes

Mathematics Subject Classification ID

Problems related to evolution (92D15) Protein sequences, DNA sequences (92D20) Pathology, pathophysiology (92C32)

Cited In (6)

• Recursive partitioning of resistant mutations for longitudinal markers based on a U-type score
• Parameter estimation from single patient, single time-point sequencing data of recurrent tumors
• On statistical modeling of sequencing noise in high depth data to assess tumor evolution
• MoTERNN: classifying the mode of cancer evolution using recursive neural networks
• TreeMHN
• A novel multiscale framework for delineating cancer evolution from subclonal compositions

Uses Software

• SCARLET
• pathTiMEx
• BiTSC2
• SiFit

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