Parsimonious Clone Tree Reconciliation in Cancer.

DOI10.4230/LIPICS.WABI.2021.9zbMATH Open1519.92172OpenAlexW3185818315MaRDI QIDQ6133871FDOQ6133871

Authors: Palash Sashittal, Simone Zaccaria, Mohammed El-Kebir 

Publication date: 24 July 2023

Full work available at URL: https://doi.org/10.4230/lipics.wabi.2021.9

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• TreeClone: reconstruction of tumor subclone phylogeny based on mutation pairs using next generation sequencing data
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zbMATH Keywords

phylogeneticsmixed integer linear programmingintra-tumor heterogeneity

Mathematics Subject Classification ID

Protein sequences, DNA sequences (92D20) Mixed integer programming (90C11) Computational methods for problems pertaining to biology (92-08) Pathology, pathophysiology (92C32)

Cited In (7)

• TreeClone: reconstruction of tumor subclone phylogeny based on mutation pairs using next generation sequencing data
• Reconstructing mutational history in multiply sampled tumors using perfect phylogeny mixtures
• Joint analysis of single-cell and bulk tissue sequencing data to infer intratumor heterogeneity
• RNDClone: tumor subclone reconstruction based on integrating DNA and RNA sequence data
• Ancestral inference in tumors: how much can we know?
• Tumor copy number deconvolution integrating bulk and single-cell sequencing data
• Copy-number evolution problems: complexity and algorithms

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