Combinatorial optimization in rapidly mutating drug-resistant viruses

DOI10.1023/A:1009846028730zbMATH Open0959.92013OpenAlexW2126676378MaRDI QIDQ1306407FDOQ1306407

Authors: Richard H. Lathrop, Michael J. Pazzani 

Publication date: 21 November 1999

Published in: Journal of Combinatorial Optimization (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1023/a:1009846028730

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zbMATH Keywords

HIVartificial intelligencemutationsdrug resistancemutantsexpert systemvirusesretrovirusclinical treatment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Applications of mathematical programming (90C90) Combinatorial optimization (90C27)

Cited In (2)

• Escaping stochastic extinction of mutant virus: temporal pattern of emergence of drug resistance within a host
• Antibiotics time machines are hard to build

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