The influence of higher-order epistasis on biological fitness landscape topography

DOI10.1007/s10955-018-1975-3zbMath1396.92054OpenAlexW2950308590WikidataQ55002438 ScholiaQ55002438MaRDI QIDQ1668973

Daniel M. Weinreich, Jacob Jaffe, Robert B. Heckendorn, Yinghong Lan

Publication date: 29 August 2018

Published in: Journal of Statistical Physics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10955-018-1975-3

zbMATH Keywords

natural selectionfitness landscapes topographyhigher-order epistasisNK landscapesequence space combinatorics

Mathematics Subject Classification ID

Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (3)

Higher-Order Interactions in Biology: The Curious Case of Epistasis ⋮ Pairwise and higher-order epistatic effects among somatic cancer mutations across oncogenesis ⋮ An uncertainty law for microbial evolution

Uses Software

• Matlab

Cites Work

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• Fourier and Taylor series on fitness landscapes
• Random field models for fitness landscapes
• Landscapes and their correlation functions
• On the evolutionary effect of recombination
• Exact results for amplitude spectra of fitness landscapes
• The Biochemical Architecture of an Ancient Adaptive Landscape
• Quantitative analyses of empirical fitness landscapes
• A NEW MEASURE OF RANK CORRELATION

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