Fixed points and connections between positive and negative cycles in Boolean networks

DOI10.1016/J.DAM.2017.12.037zbMATH Open1387.05244arXiv1509.07702OpenAlexW2962714361MaRDI QIDQ1752437FDOQ1752437

Authors: Adrien Richard 

Publication date: 24 May 2018

Published in: Discrete Applied Mathematics (Search for Journal in Brave)

Abstract: We are interested in the relationships between the number fixed points in a Boolean network $f:{0,1}^{n}o{0,1}^n$ and its interaction graph, which is the arc-signed digraph $G$ on $1,dots,n$ that describes the positive and negative influences between the components of the network. A fundamental theorem of Aracena says that if $G$ has no positive (resp. negative) cycle, then $f$ has at most (resp. at least) one fixed point; the sign of a cycle being the product of the signs of its arcs. In this note, we generalize this result by taking into account the influence of connections between positive and negative cycles. In particular, we prove that if every positive (resp. negative) cycle of $G$ has an arc $a$ such that $Gsetminusa$ has a non-trivial initial strongly connected component containing the terminal vertex of $a$ and only negative (resp. positive) cycles, then $f$ has at most (resp. at least) one fixed point. This is, up to our knowledge, the first generalization of Aracena's theorem where the conditions are expressed with $G$ only.

Full work available at URL: https://arxiv.org/abs/1509.07702

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zbMATH Keywords

fixed pointBoolean networkinteraction graphnegative cyclepositive cycle

Mathematics Subject Classification ID

Directed graphs (digraphs), tournaments (05C20) Deterministic network models in operations research (90B10) Small world graphs, complex networks (graph-theoretic aspects) (05C82)

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Cited In (23)

• Counting periodic points in parallel graph dynamical systems
• Sequentialization and procedural complexity in automata networks
• On Fixable Families of Boolean Networks
• From kernels in directed graphs to fixed points and negative cycles in Boolean networks
• Graphic requirements for multistability and attractive cycles in a Boolean dynamical framework
• Nilpotent dynamics on signed interaction graphs and weak converses of Thomas' rules
• Topological fixed points in Boolean networks
• Positive circuits and maximal number of fixed points in discrete dynamical systems
• Local negative circuits and fixed points in non-expansive Boolean networks
• Fixed point theorems for Boolean networks expressed in terms of forbidden subnetworks
• A general model of binary opinions updating
• Number of fixed points and disjoint cycles in monotone Boolean networks
• Characterisation of the elementary cellular automata in terms of their maximum sensitivity to all possible asynchronous updates
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• Complexity of fixed point counting problems in Boolean networks
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• Fixed points of Boolean networks, guessing graphs, and coding theory
• Positive and negative cycles in Boolean networks
• Attractor separation and signed cycles in asynchronous Boolean networks
• A fixed point theorem for Boolean networks expressed in terms of forbidden subnetworks
• Negative local feedbacks in Boolean networks
• Linear cuts in Boolean networks
• Local cycles and dynamical properties of Boolean networks

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