The kientics of bivalent ligand-bivalent receptor aggregation: Ring formation and the breakdown of the equivalent site approximation
DOI10.1016/0025-5564(94)00045-2zbMATH Open0820.92007OpenAlexW1997857545WikidataQ72126394 ScholiaQ72126394MaRDI QIDQ1804830FDOQ1804830
Authors: Richard G. Posner, Carla Wofsy, Byron Goldstein 
Publication date: 14 September 1995
Published in: Mathematical Biosciences (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/0025-5564(94)00045-2
Recommendations
ring formationinfinite set of coupled ordinary differential equationsbivalent ligandsaggregate size distributionbivalent receptorschain formationkinetics of aggregate formationligand concentrationsring concentrationssite approximation
Biochemistry, molecular biology (92C40) Physiology (general) (92C30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) General theory for ordinary differential equations (34A99)
Cites Work
- Analysis of a molecular signal for cell function in algebraic reactions
- Theory of equilibrium binding of a bivalent ligand to cell surface antibody: The effect of antibody heterogeneity on cross-linking
- Receptor clustering on a cell surface. I. Theory of receptor cross- linking by ligands bearing two chemically identical functional groups
- Receptor clustering on a cell surface. II. Theory of receptor cross- linking by ligands bearing two chemically distinct functional groups
Cited In (9)
- Title not available (Why is that?)
- Ring formation in divalent-receptor-divalent-ligand interaction: Pseudocooperative shapes of Scatchard plots
- Analysis of biochemical equilibria relevant to the immune response: finding the dissociation constants
- Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density
- Antagonist binding in the rat muscarinic receptor: A study by docking and X-ray crystallogra\-phy
- Generalized concentration addition for ligands that bind to homodimers
- On the interaction of different types of ligands binding to the same molecule part II: systems with \(n\) to 2 and \(n\) to 3 binding sites
- Interpretation of Scatchard plots for aggregating receptor systems
- Diffusion theory can be applied to antibodies attaching to ligand sites
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