Topological analysis of metabolic control

DOI10.1016/0025-5564(90)90062-4zbMath0788.92008WikidataQ45384586 ScholiaQ45384586MaRDI QIDQ1813608

Asok K. Sen

Publication date: 25 June 1992

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(90)90062-4

zbMATH Keywords

weighted directed graph; metabolic pathways; feedback inhibition; topological approach; metabolic regulation; cause-effect relationships; unbranched pathway; absence of feedback; control coefficients of the enzymes; enzyme elasticities; feedforward regulation

Mathematics Subject Classification ID

93C95: Application models in control theory

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C40: Biochemistry, molecular biology

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Cites Work

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• A comparison of variant theories of intact biochemical systems. I: Enzyme-enzyme interactions and biochemical systems theory
• A comparison of variant theories of intact biochemical systems. II: Flux- oriented and metabolic control theories
• Biochemical systems theory and metabolic control theory: I. Fundamental similarities and differences
• Biochemical systems theory and metabolic control theory: II. The role of summation and connectivity relationships
• Use of implicit methods from general sensitivity theory to develop a systematic appoach to metabolic control. I: Unbranched pathways
• Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. II: Complex systems