Biochemical systems theory and metabolic control theory: I. Fundamental similarities and differences

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The paper is a lengthy explication of a priority affair - without too much mathematics concerned. The main statement is that a conceptual framework called biochemical systems theory (BST, for short) has been developed for the modelling of intact biochemical systems mainly by the first author [J. Theor. Biol. 25, 365-379 (1969), and ibid. 26, 215-226 (1970)]. Representants of metabolic control theory, however, seem to consciously neglect these results, or they rediscover special statements of BST. The paper itself also includes arguments against the authors' view: Eq. (9) is clearly more general then Eq. (8). It is also true that fundamental works of deterministic mass action kinetics where all the topics really belong to are almost totally neglected.




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