Age structure can account for delayed logistic proliferation of scratch assays

DOI10.1007/S11538-019-00625-WzbMATH Open1417.92027OpenAlexW2952388590WikidataQ70867792 ScholiaQ70867792MaRDI QIDQ2002133FDOQ2002133

T. Carraro, Philip K. Maini, H. M. Byrne, Tomás Alarcón, Ana Victoria Ponce Bobadilla

Publication date: 11 July 2019

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://ora.ox.ac.uk/objects/uuid:b6901d67-9cfc-4415-868e-3a07ba89898b

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zbMATH Keywords

cell proliferationscratch assayage-structured modellogistic growth modelvon Foerster-McKendrick type model

Mathematics Subject Classification ID

Developmental biology, pattern formation (92C15) Cell biology (92C37)

Cites Work

• deal.II—A general-purpose object-oriented finite element library
• The McKendrick partial differential equation and its uses in epidemiology and population study
• Age-structured cell population model to study the influence of growth factors on cell cycle dynamics
• The contribution of age structure to cell population responses to targeted therapeutics
• Travelling waves in a wound healing assay.
• Reproducibility of scratch assays is affected by the initial degree of confluence: experiments, modelling and model selection
• Stochastic multi-scale models of competition within heterogeneous cellular populations: simulation methods and mean-field analysis
• Designing proliferating cell population models with functional targets for control by anti-cancer drugs
• Numerical treatment of partial differential equations. Revised translation of the 3rd German edition of `Numerische Behandlung partieller Differentialgleichungen' by Martin Stynes.
• A comparison and catalog of intrinsic tumor growth models
• Extended logistic growth model for heterogeneous populations
• Structured models of cell migration incorporating molecular binding processes
• Logistic proliferation of cells in scratch assays is delayed
• A Bayesian computational approach to explore the optimal duration of a cell proliferation assay
• The invasion speed of cell migration models with realistic cell cycle time distributions
• Investigation of a Structured Fisher's Equation with Applications in Biochemistry

Cited In (3)

• Dynamics of an expanding cell monolayer
• Negligible long-term impact of nonlinear growth dynamics on heterogeneity in models of cancer cell populations
• Population dynamics with threshold effects give rise to a diverse family of allee effects

Uses Software

• deal.ii

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