Quantifying the impact of changes in effective population size and expression level on the rate of coding sequence evolution

DOI10.1016/J.TPB.2021.09.005MaRDI QIDQ2076092zbMATH OpenOpenAlexFDO

Authors T. Latrille, Nicolas Lartillot

Publication date 18 February 2022

Published in Theoretical Population Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.tpb.2021.09.005

zbMATH Keywords

driftexpression levelpopulation-geneticsprotein stabilitysubstitution rate

Mathematics Subject Classification ID

Problems related to evolution (92D15)

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Cites work

• Model of effectively neutral mutations in which selective constraint is incorporated

Cited in

(4)

• The role of population size in molecular evolution
• Selection in favor of nucleotides G and C diversifies evolution rates and levels of polymorphism at mammalian synonymous sites
• Selection maintaining protein stability at equilibrium
• Fluctuations in fitness distributions and the effects of weak linked selection on sequence evolution

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