Selection in favor of nucleotides G and C diversifies evolution rates and levels of polymorphism at mammalian synonymous sites

DOI10.1016/J.JTBI.2005.10.020MaRDI QIDQ2202183zbMATH OpenOpenAlexWikidataFDO

Authors Fyodor A. Kondrashov, Aleksey Y. Ogurtsov, Alexey S. Kondrashov

Publication date 17 September 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2005.10.020

zbMATH Keywords

selectionevolutionmutationgenetic driftsynonymous site

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cited in

(4)

• On parameters of the human genome
• The level of cytosine is usually much higher than the level of guanine in two-fold degenerated sites from third codon positions of genes from simplex- and varicelloviruses with G\(+\)C higher than 50\%
• Selection maintaining protein stability at equilibrium
• POSITIVE DARWINIAN SELECTION: DOES THE COMPARATIVE METHOD RULE?

Describes a project that uses

Uses Software

• CpG island searcher
• PAML

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