Genetic codes as evolutionary filters: subtle differences in the structure of genetic codes result in significant differences in patterns of nucleotide substitution

DOI10.1016/J.JTBI.2003.09.019MaRDI QIDQ2187495zbMATH OpenOpenAlexWikidataFDO

Authors David A. McClellan, D. G. Whiting, Ryan Christensen, Joshua Sailsbery

Publication date 3 June 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2003.09.019

zbMATH Keywords

molecular evolutioncodon-degeneracygenetic codestransition biastransition-to-transversion ratio

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

Recommendations

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Cited in

(3)

• Codon information value and codon transition-probability distributions in short-term evolution
• Selection in favor of nucleotides G and C diversifies evolution rates and levels of polymorphism at mammalian synonymous sites
• Many alternative and theoretical genetic codes are more robust to amino acid replacements than the standard genetic code

Describes a project that uses

Uses Software

• TreeSAAP
• PAML

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