A multiscale model to design therapeutic strategies that overcome drug resistance to tyrosine kinase inhibitors in multiple myeloma

DOI10.1016/j.mbs.2019.108293zbMath1437.92059OpenAlexW2992874540WikidataQ91758580 ScholiaQ91758580MaRDI QIDQ2173889

Anass Bouchnita, Mark J. Koury, Andreas Hellander, Vitaly A. Volpert

Publication date: 17 April 2020

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2019.108293

zbMATH Keywords

targeted therapypentose phosphate pathwaycell metabolismgefitinibtyrosine kinase inhibitor

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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Phenotype-structured model of intra-clonal heterogeneity and drug resistance in multiple myeloma

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