Phenotype-structured model of intra-clonal heterogeneity and drug resistance in multiple myeloma

DOI10.1016/j.jtbi.2023.111652OpenAlexW4388562527MaRDI QIDQ6192824

Vitaly A. Volpert, Anass Bouchnita

Publication date: 13 February 2024

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2023.111652

zbMATH Keywords

chemotherapycontinuum modelingclone emergenceIRF4RAS mutations

Mathematics Subject Classification ID

Pathology, pathophysiology (92C32)

Cites Work

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• A multiscale model to design therapeutic strategies that overcome drug resistance to tyrosine kinase inhibitors in multiple myeloma
• Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy
• Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model
• A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion

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