Dynamical system analysis of a Lassa fever model with varying socioeconomic classes

DOI10.1155/2020/2601706MaRDI QIDQ2228294zbMATH OpenOpenAlexFDO

Authors Ifeanyi Sunday Onah, Obiora Cornelius Collins

Publication date 17 February 2021

Published in Journal of Applied Mathematics (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1155/2020/2601706

Mathematics Subject Classification ID

Epidemiology (92D30)

Review text

Summary: Lassa fever is an animal-borne acute viral illness caused by Lassa virus. It poses a serious health challenge around the world today, especially in West African countries like Ghana, Benin, Guinea, Liberia, Mali, Sierra Leone, and Nigeria. In this work, we formulate a multiple-patch Lassa fever model, where each patch denotes a socioeconomic class (SEC). Some of the important epidemiological features such as basic reproduction number of the model were determined and analysed accordingly. We further investigated how varying SECs affect the transmission dynamics of Lassa fever. We analysed the required state at which each SEC is responsible in driving the Lassa fever disease outbreak. Sensitivity analyses were carried out to determine the importance of model parameters to the disease transmission and prevalence. We carried out numerical simulation to support our analytical results. Finally, we extend some of the results of the 2-patch model to the general \(n\)-patch model.

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Cites work

• Analysis of a waterborne disease model with socioeconomic classes
• Dynamical system analysis and optimal control measures of Lassa fever disease model
• Mathematical modelling and analysis of transmission dynamics of Lassa fever
• Mechanistic modelling of the large-scale Lassa fever epidemics in Nigeria from 2016 to 2019
• Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission
• The type-reproduction number \(T\) in models for infectious disease control

Cited in

(9)

• Modeling the dynamics of Lassa fever in Nigeria
• Approximate solution of the fractional order sterile insect technology model via the Laplace-Adomian decomposition method for the spread of Zika virus disease
• Modeling, analyzing and simulating the dynamics of Lassa fever in Nigeria
• Modelling the transmission dynamics of lassa fever with nonlinear incidence rate and vertical transmission
• Mechanistic modelling of the large-scale Lassa fever epidemics in Nigeria from 2016 to 2019
• Unravelling the dynamics of Lassa fever transmission with differential infectivity: modeling analysis and control strategies
• Analysis and optimal control measures of diseases in cassava population
• A systematic review of mathematical models of Lassa fever
• Dynamical system analysis and optimal control measures of Lassa fever disease model

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