Spike-and-slab Lasso biclustering

DOI10.1214/20-AOAS1385MaRDI QIDQ2233147zbMATH OpenOpenAlexFDO

Authors Gemma E. Moran, Veronika Rockova, Edward I. George

Publication date 14 October 2021

Published in The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1214/20-aoas1385

zbMATH Keywords

Bayesbiclusteringfactor analysishierarchical modelingspike-and-slab Lassovariable selection

Mathematics Subject Classification ID

Bayesian inference (62F15) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Ridge regression; shrinkage estimators (Lasso) (62J07) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Review text

The main contribution of this paper is the so-called spike-and-slab Lasso biclustering method. Using previous results by the authors, the proposed biclustering approach is able to effectivly find a sparse factorization of the data matrix. Two real datasets, a microarray dataset and a single-cell RNA-sequencing dataset, are employed to demonstrate the efficiency of biclustering to derive the interpretable solutions.

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Cites work

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• scientific article; zbMATH DE number 3349081 (Why is no real title available?)
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Cited in

(13)

• Biclustering via structured regularized matrix decomposition
• Profile likelihood biclustering
• Biclustering via sparse singular value decomposition
• Biclustering via sparse clustering
• SSLB
• Uncovering block structures in large rectangular matrices
• Co-clustering of spatially resolved transcriptomic data
• Comment: Regularization via Bayesian Penalty Mixing
• Estimating sparse direct effects in multivariate regression with the spike-and-slab LASSO
• Posterior contraction and uncertainty quantification for the multivariate spike-and-slab LASSO
• Outcome-guided spike-and-slab Lasso biclustering: a novel approach for enhancing biclustering techniques for gene expression analysis
• Toward Interpretable Deep Generative Models via Causal Representation Learning
• Knowledge-guided Bayesian biclustering model for omics data with noisy graphs

Describes a project that uses

Uses Software

• COSA
• LAS
• breastCancerNKI
• clusterProfiler
• FABIA
• GitHub

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