Virulence of a virus: how it depends on growth rate, effectors, memory cells, and immune escape

DOI10.1016/J.JTBI.2021.110875MaRDI QIDQ2235527zbMATH OpenOpenAlexFDO

Authors Yoh Iwasa, Akane Hara, Shihomi Ozone

Publication date 21 October 2021

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.jtbi.2021.110875

zbMATH Keywords

mutationcytotoxic T cellsmemory T cellsviral growth rate

Mathematics Subject Classification ID

Pathology, pathophysiology (92C32)

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Cites work

• scientific article; zbMATH DE number 2038872 (Why is no real title available?)
• Autoimmune diseases initiated by pathogen infection: mathematical modeling
• Directed Technical Change
• Dynamic optimization of host defense, immune memory, and post-infection pathogen levels in mammals

Cited in

(3)

• Viral rebound occurrence immediately after drug discontinuation involving neither drug resistance nor latent reservoir
• Temporal pattern of the emergence of a mutant virus escaping cross-immunity and stochastic extinction within a host
• Escaping stochastic extinction of mutant virus: temporal pattern of emergence of drug resistance within a host

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