Stochastic modeling of the neuronal activity in the subthalamic nucleus and model parameter identification from Parkinson patient data

DOI10.1007/S00422-010-0397-3MaRDI QIDQ2376510zbMATH OpenOpenAlexDBLPWikidataFDO

Authors Ishita Basu, Daniel Graupe, Daniela Tuninetti, Konstantin V. Slavin

Publication date 21 June 2013

Published in Biological Cybernetics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00422-010-0397-3

zbMATH Keywords

inter-spike intervalOrnstein-Uhlenbeck processparameter identificationParkinson's diseasestochastic modelingsubthalamic nucleus

Mathematics Subject Classification ID

Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Probabilistic models, generic numerical methods in probability and statistics (65C20) Neural biology (92C20) Medical applications (general) (92C50)

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Cites work

• A new integral equation for the evaluation of first-passage-time probability densities
• Diffusion approximation and first passage time problem for a model neuron
• First-passage-time density and moments of the ornstein-uhlenbeck process
• scientific article; zbMATH DE number 3880504 (Why is no real title available?)
• Maximum Likelihood Estimation of Parameters in the Inverse Gaussian Distribution, with Unknown Origin
• Nonparametric statistics for non-statisticians: a step-by-step approach
• On the histogram as a density estimator:L 2 theory
• On the parameter estimation for diffusion models of single neuron's activities. I: Application to spontaneous activities of mesencephalic reticular formation cells in sleep and waking states
• The Ornstein-Uhlenbeck process as a model for neuronal activity. I. Mean and variance of the firing time
• Towards model-based control of Parkinson's disease

Cited in

(4)

• Mean-field modeling of the basal ganglia-thalamocortical system. II: Dynamics of Parkinsonian oscillations
• A single compartment model of pacemaking in dissasociated substantia nigra neurons. Stability and energy analysis
• A biophysical model of the cortex-basal ganglia-thalamus network in the 6-OHDA lesioned rat model of Parkinson's disease
• BLENX MODELS OF α-SYNUCLEIN AND PARKIN KINETICS IN NEUROPATHOLOGY OF PARKINSON'S DISEASE

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