Calculation errors of time-varying flux control coefficients obtained from elasticity coefficients by means of summation and connectivity theorems in metabolic control analysis

DOI10.1016/J.MBS.2009.11.004MaRDI QIDQ2379632zbMATH OpenOpenAlexWikidataFDO

Authors Fumihide Shiraishi, Kansuporn Sriyudthsak, Yusuke Suzuki

Publication date 19 March 2010

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL http://hdl.handle.net/2324/26584

zbMATH Keywords

dynamic sensitivityelasticity coefficientfed-batch fermentation processpenicillin Vtime-varying flux control coefficient

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Dynamical systems in biology (37N25) Computational methods for problems pertaining to biology (92-08) Physiology (general) (92C30)

Recommendations

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Cites work

• A simple and highly accurate numerical differentiation method for sensitivity analysis of large-scale metabolic reaction systems
• An efficient method for calculation of dynamic logarithmic gains in biochemical systems theory
• Computation and analysis of time-dependent sensitivities in generalized mass action systems
• Dynamic sensitivities in chaotic dynamical systems
• Sensitivity analysis of stoichiometric networks: an extension of metabolic control analysis to non-steady state trajectories

Cited in

(3)

• Application of computer algebra-techniques to metabolic control analysis
• Biochemical systems theory: a review
• Highly accurate computation of dynamic sensitivities in metabolic reaction systems by a Taylor series method

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