The benefits of diversity: heterogenous DC populations allow for both immunity and tolerance

DOI10.1016/J.JTBI.2014.04.034zbMATH Open1412.92053OpenAlexW1976265964WikidataQ51088403 ScholiaQ51088403MaRDI QIDQ2415604FDOQ2415604

Authors: James R. Moore 

Publication date: 23 May 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2014.04.034

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zbMATH Keywords

interleukin-2autoimmunityregulatory T-cellsT-cell: APC interactiontolerogenic dendritic cells

Mathematics Subject Classification ID

Physiology (general) (92C30)

Cites Work

• Modeling Cyclic Waves of Circulating T Cells in Autoimmune Diabetes
• Autoimmunity arising from bystander proliferation of T cells in an immune response model
• Self-tolerance and autoimmunity in a regulatory T cell model
• Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making
• Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease?
• Th1/Th2 differentiation and cross-regulation
• Tolerance and immunity in a mathematical model of T-cell mediated suppression
• Dynamical properties of autoimmune disease models: tolerance, flare-up, dormancy

Cited In (1)

• A mathematical model of T1D acceleration and delay by viral infection

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