A mathematical model of T1D acceleration and delay by viral infection

DOI10.1007/s11538-016-0152-6zbMath1343.92502OpenAlexW2326945959WikidataQ40734921 ScholiaQ40734921MaRDI QIDQ300638

James R. Moore, Fred Adler

Publication date: 28 June 2016

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-016-0152-6

zbMATH Keywords

autoimmune diseasedendritic cellsT-cellsTregstype 1 diabetesviral infection

Mathematics Subject Classification ID

Epidemiology (92D30) Medical epidemiology (92C60)

Cites Work

• Continuum model of T-cell avidity: understanding autoreactive and regulatory T-cell responses in type 1 diabetes
• The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation
• The benefits of diversity: heterogenous DC populations allow for both immunity and tolerance
• Self-tolerance and autoimmunity in a regulatory T cell model
• Modeling dynamic changes in type 1 diabetes progression: quantifying \(\beta\)-cell variation after the appearance of islet-specific autoimmune responses
• Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease?
• Modeling Cyclic Waves of Circulating T Cells in Autoimmune Diabetes

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