Optimal policies of non-cross-resistant chemotherapy on Goldie and Coldman's cancer model

DOI10.1016/j.mbs.2013.07.020zbMath1308.92047OpenAlexW2070186352WikidataQ51175423 ScholiaQ51175423MaRDI QIDQ2437023

Jeng-Huei Chen, Hsing Paul Luh, Ya-Hui Kuo

Publication date: 27 February 2014

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2013.07.020

zbMATH Keywords

drug resistanceGoldie and Coldman's modeloptimal cancer treatment

Mathematics Subject Classification ID

Medical applications (general) (92C50)

Related Items

Optimal therapy scheduling based on a pair of collaterally sensitive drugs

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• The mathematical modelling of adjuvant chemotherapy scheduling: incorporating the effects of protocol rest phases and pharmacokinetics
• The worst drug rule revisited: mathematical modeling of cyclic cancer treatments
• Tutorials in mathematical biosciences III. Cell cycle, prolifereation, and cancer.
• Role of optimal control theory in cancer chemotherapy
• A model for the resistance of tumor cells to cancer chemotherapeutic agents
• A theoretical analysis of interval drug dosing for cell-cycle-phase- specific drugs
• Time-continuous branching walk models of unstable gene amplification
• Singularity of optimal control in some problems related to optimal chemotherapy
• The effect of heterogeneity on optimal regimens in cancer chemotherapy
• A mathematical model to study the effects of drug resistance and vasculature on the response of solid tumors to chemotherapy
• Sufficient conditions for relative minima of broken extremals in optimal control theory
• Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
• Cancer chemotherapy optimization under evolving drug resistance.
• The application of mathematical modelling to aspects of adjuvant chemotherapy scheduling
• Stochastic modeling of drug resistance in cancer
• The dynamics of gene amplification described as a multitype compartmental model and as a branching process
• The High Order Maximal Principle and Its Application to Singular Extremals
• ANALYSIS OF A CELL-CYCLE SPECIFIC MODEL FOR CANCER CHEMOTHERAPY