The dynamics of gene amplification described as a multitype compartmental model and as a branching process

DOI10.1016/0025-5564(91)90094-YMaRDI QIDQ2277181zbMATHOpenAlexWikidataFDO

Authors L. E. Harnevo, Zvia Agur

Publication date 1991

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(91)90094-y

zbMATH Keywords

probability generating functionmultitype branching processdifference equationsdrug resistanceGalton-Watson processexpectation matrixtreatment of cancera.s. extinctiondrug sensitive cellsdynamics of gene amplification

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Applications of branching processes (60J85)

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• Dynamics of cancer recurrence
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• On the probability of random genetic mutations for various types of tumor growth

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