Steric hindrance effects on surface reactions: applications to bIAcore

DOI10.1007/S00285-007-0093-7MaRDI QIDQ2460436zbMATH OpenOpenAlexWikidataFDO

Authors David A. Edwards

Publication date 12 November 2007

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-007-0093-7

zbMATH Keywords

BIA coresurface volume

Mathematics Subject Classification ID

Perturbations in context of PDEs (35B20) Integral representations of solutions to PDEs (35C15) Heat equation (35K05) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Review text

The author presents some general mathematical principles for handling steric hindrance effect and a surface reaction model using mathematical model. The model developed has been experimented by a number of numerical experiments for illustration.

Recommendations

• Steric hindrance effects in thin reaction zones: applications to BIAcore
• Modeling of the surface-reaction diffusion and numerical solution
• Surface Reaction Near a Stagnation Point
• Refining the measurement of rate constants in the BIAcore
• Convection Effects in Thin Reaction Zones: Applications to Biacore

Cites work

• Asymptotic analysis of dissolution of a spherical bubble (case of fast reaction outside the bubble)
• Convection effects in the BIAcore dextran layer: surface reaction model
• Estimating rate constants in a convection-diffusion system with a boundary reaction
• Lattice Boltzmann Simulation of Diffusion-Convection Systems with Surface Chemical Reaction
• Testing the validity of the effective rate constant approximation for surface reaction with transport
• The effect of a receptor layer on the measurement of rate constants
• The effect of receptor site nonuniformity on the measurement of rate constants
• Transport effects on surface-volume biological reactions

Cited in

(3)

• A linear model for polyclonal antibody-antigen reactions
• Modelling random antibody adsorption and immunoassay activity
• Steric hindrance effects in thin reaction zones: applications to BIAcore

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