Principles of rapid polymerase chain reactions: mathematical modeling and experimental verification

DOI10.1016/J.COMPBIOLCHEM.2004.03.001MaRDI QIDQ2490595zbMATH OpenOpenAlexWikidataFDO

Authors Scott E. Whitney, Alugupally Sudhir, R. Michael Nelson, H. J. Viljoen

Publication date 16 May 2006

Published in Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.compbiolchem.2004.03.001

zbMATH Keywords

Biochemical engineeringMolecular biologyPolymerase chain reaction

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cited in

(14)

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• Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems
• A general model of error-prone PCR
• The polymerase chain reaction model analyzed by the homotopy perturbation method
• A macroscopic kinetic model for DNA polymerase elongation and high-fidelity nucleotide selection
• A quantitative model of error accumulation during PCR amplification
• scientific article; zbMATH DE number 1094274 (Why is no real title available?)
• Kinetic characteristics of continuous flow polymerase chain reaction chip: a numerical investigation
• Enzymological description of multitemplate PCR -- shrinking amplification bias by optimizing the polymerase-template ratio
• A general probabilistic model of the PCR process
• Rapid microfluidic thermal cycler for polymerase chain reaction nucleic acid amplification

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