A mathematical model of the impact of novel treatments on the A burden in the Alzheimer's brain, CSF and plasma

DOI10.1006/BULM.2002.0304zbMATH Open1334.92068OpenAlexW4250104128WikidataQ44188170 ScholiaQ44188170MaRDI QIDQ253301FDOQ253301

Authors: D. Craft, Lawrence M. Wein, Dennis J. Selkoe 

Publication date: 8 March 2016

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1006/bulm.2002.0304

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zbMATH Keywords

Alzheimer's diseaseamyloid-betacerebrospinal fluidpolymerization ratio

Mathematics Subject Classification ID

Neural biology (92C20)

Cited In (9)

• A continuous-time mathematical model and discrete approximations for the aggregation of β-Amyloid
• Stability analysis of a steady state of a model describing Alzheimer's disease and interactions with prion proteins
• Modeling the interaction between \(\beta\)-amyloid aggregates and choline acetyltransferase activity and its relation with cholinergic dysfunction through two-enzyme/two-compartment model
• Alzheimer's disease: analysis of a mathematical model incorporating the role of prions
• Development of \(\mathrm{A}\beta\) and anti-\(\mathrm{A}\beta\) dynamics models for Alzheimer's disease
• The amyloid cascade hypothesis and Alzheimer’s disease: A mathematical model
• The synergistic interplay of Amyloid beta and tau proteins in Alzheimer's disease: a compartmental mathematical model
• Modeling effect of a \(\gamma \)-secretase inhibitor on amyloid-\(\beta \) dynamics reveals significant role of an amyloid clearance mechanism
• Modeling the spatial propagation of Aβ oligomers in Alzheimer’s Disease

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