Robustness analysis of elementary flux modes generated by column generation

DOI10.1016/J.MBS.2015.12.009zbMATH Open1360.92050OpenAlexW2200940591WikidataQ40126377 ScholiaQ40126377MaRDI QIDQ254086FDOQ254086

Authors: Hildur Æsa Oddsdóttir, Erika Hagrot, Véronique Chotteau, Anders Forsgren 

Publication date: 8 March 2016

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2015.12.009

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zbMATH Keywords

least-squaresChinese hamster ovary cellelementary flux modemetabolic networkrobust optimization

Mathematics Subject Classification ID

Applications of mathematical programming (90C90) Biochemistry, molecular biology (92C40) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• Maximizing Submodular Set Functions: Formulations and Analysis of Algorithms
• Robust optimization
• Robust Solutions to Least-Squares Problems with Uncertain Data
• Robust Optimization of Large-Scale Systems
• Selected Topics in Column Generation
• Fast computation of minimal elementary decompositions of metabolic flux vectors

Cited In (3)

• Stabilized column generation
• A simplex approach to solving robust metabolic models with low-dimensional uncertainty
• An interval approach for dealing with flux distributions and elementary modes activity patterns

Uses Software

• EFMEvolver
• Metatool

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