Likelihood-ratio-test methods for drug safety signal detection from multiple clinical datasets

DOI10.1155/2019/1526290MaRDI QIDQ2632243zbMATH OpenOpenAlexWikidataFDO

Authors Lan Huang, Jyoti N. Zalkikar, Ram C. Tiwari

Publication date 14 May 2019

Published in Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1155/2019/1526290

zbMATH Keywords

clinical datasetsdrug safety signal detectionlikelihood-ratio-test

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

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Cites work

• scientific article; zbMATH DE number 1817585 (Why is no real title available?)
• A likelihood ratio test based method for signal detection with application to FDA's drug safety data
• Introduction to Meta‐Analysis

Cited in

(5)

• Multivariate Tests Comparing Binomial Probabilities, with Application to Safety Studies for Drugs
• A likelihood ratio test based method for signal detection with application to FDA's drug safety data
• Accounting for Multiplicities in Assessing Drug Safety: A Three-Level Hierarchical Mixture Model
• False Discovery Rate Estimation for Frequentist Pharmacovigilance Signal Detection Methods
• Efficient methods for signal detection from correlated adverse events in clinical trials

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