A new protocol for intermittent androgen suppression therapy of prostate cancer with unstable saddle-point dynamics

DOI10.1016/J.JTBI.2014.02.004MaRDI QIDQ2632781zbMATH OpenOpenAlexWikidataFDO

Authors Yasuyuki Suzuki, Daichi Sakai, Taishin Nomura, Yoshito Hirata, Kazuyuki Aihara

Publication date 15 May 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2014.02.004

zbMATH Keywords

hybrid dynamical systemintermittent androgen suppressionintermittent controlmathematical modelprostate cancer

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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Cites work

• A mathematical model of intermittent androgen suppression for prostate cancer
• A mathematical model of prostate tumor growth under hormone therapy with mutation inhibitor
• A model at the macroscopic scale of prostate tumor growth under intermittent androgen suppression
• A nonlinear model with competition between prostate tumor cells and its application to intermittent androgen suppression therapy of prostate cancer
• A partial differential equation model and its reduction to an ordinary differential equation model for prostate tumor growth under intermittent hormone therapy
• Analysis of chattering in continuous sliding-mode controllers
• Bifurcation analysis on a hybrid systems model of intermittent hormonal therapy for prostate cancer
• Chattering Analysis
• Development of a mathematical model that predicts the outcome of hormone therapy for prostate cancer
• Intermittent control with ankle, hip, and mixed strategies during quiet standing: a theoretical proposal based on a double inverted pendulum model
• MATHEMATICAL MODELING OF PROSTATE TUMOR GROWTH UNDER INTERMITTENT ANDROGEN SUPPRESSION WITH PARTIAL DIFFERENTIAL EQUATIONS
• Modeling prostate cancer response to continuous versus intermittent androgen ablation therapy
• Nonlinear system identification for prostate cancer and optimality of intermittent androgen suppression therapy
• Variable structure systems with sliding modes

Cited in

(13)

• Dynamics of a non-smooth model of prostate cancer with intermittent androgen deprivation therapy
• Global analysis of the dynamics of a piecewise linear vector field model for prostate cancer treatment
• Dynamics and implications of models for intermittent androgen suppression therapy
• Practically scheduling hormone therapy for prostate cancer using a mathematical model
• Optimal design of personalized prostate cancer therapy using infinitesimal perturbation analysis
• Nonlinear system identification for prostate cancer and optimality of intermittent androgen suppression therapy
• Comment
• Mathematical modeling of continuous and intermittent androgen suppression for the treatment of advanced prostate cancer
• Hybrid optimal scheduling for intermittent androgen suppression of prostate cancer
• Optimization therapy by coupling intermittent androgen suppression with impulsive chemotherapy for a prostate cancer model
• Selection of prostate cancer therapy strategy under early androgen suppression treatment
• A joint-threshold Filippov model describing the effect of intermittent androgen-deprivation therapy in controlling prostate cancer
• Ability of intermittent androgen suppression to selectively create a non-trivial periodic orbit for a type of prostate cancer patients

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