How the number of alleles influences gene expression

DOI10.1007/S10955-006-9218-4MaRDI QIDQ2641402zbMATH OpenOpenAlexFDO

Authors Beata Hat, Pawel Paszek, Marek Kimmel, Tomasz Lipniacki, K. Piechór

Publication date 20 August 2007

Published in Journal of Statistical Physics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s10955-006-9218-4

zbMATH Keywords

stochastic gene expressionfeedback regulationChapman-Kolmogorov equationsdiploid geneshaploinsufficiencypiecewise deterministic time-continuous Markov process

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10) Signal detection and filtering (aspects of stochastic processes) (60G35) Markov processes (60J99) Cell biology (92C37)

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Cites work

• Degenerate convergence of semigroups related to a model of stochastic gene expression
• Fluctuations in transcription factor binding can explain the graded and binary responses observed in inducible gene expression
• Intrinsic and external noise in an auto-regulatory genetic network
• Intrinsic noise, gene regulation and steady-state statistics in a two-gene network
• Mathematical model of NF-\( \kappa\)B regulatory module
• Modeling stochasticity in gene regulation: Characterization in the terms of the underlying distribution function
• Multivariate analysis of noise in genetic regulatory networks
• Stability of degenerate diffusions with state-dependent switching
• Stochastic effects of multiple regulators on expression profiles in eukaryotes
• Stochastic processes in physics and chemistry.
• Transcriptional stochasticity in gene expression

Cited in

(5)

• Modeling stochasticity in gene regulation: Characterization in the terms of the underlying distribution function
• Type of noise defines global attractors in bistable molecular regulatory systems
• Gene expression in self-repressing system with multiple gene copies
• Influence of gene copy number on self-regulated gene expression
• Semigroup-theoretic approach to diffusion in thin layers separated by semi-permeable membranes

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